Mid-term outcomes after percutaneous cryoablation of symptomatic abdominal wall endometriosis: comparison with surgery alone in a single institution

Objectives To compare the outcomes of percutaneous image-guided cryoablation of symptomatic abdominal wall endometriosis (AWE) versus surgery alone.

Methods From 2004 to 2016, cryoablation or surgery alone was performed under local (n = 5) or general anaesthesia (n = 15) for AWE in a single institution in 7 (mean age, 36.1 years) and 13 (mean age, 31.9 years) patients, respectively. Fifteen lesions were treated by cryoablation (mean size, 2.3 cm; range, 0.5-7 cm) and 16 by surgery (2.5 cm; 1.1-3.4 cm). Tolerance, efficacy and patient and procedural characteristics were compared.

Results Median follow-up was 22.5 (range, 6-42) months af- ter cryoablation and 54 (14-149) after surgery. The median procedure and hospitalisation durations were 41.5 min (24- 66) and 0.8 days (0-1) after cryoablation, and 73.5 min (35- 160) and 2.8 days (1-12 days) after surgery (both P = 0.01). Three patients (23.1%) had severe complications and nine aesthetic sequels (69.2%) after surgery, none after cryoablation (P = 0.05). The median 12- and 24-month symp- tom free-survival rates were 100% and 66.7% (95% CI, 5.4; 94.5) after cryoablation and 92% (55.3; 98.9) after surgery at both time points (P = 0.45).

Conclusions Cryoablation presents similar effectiveness to surgery alone for local control of AWE while reducing hospitalisation duration and complications. Any aesthetic sequels were associated with the cryoablation treatment.

Key points

  • Hospitalisation is shorter after cryoablation than after surgery of abdominal wall endometriosis.
  • A significantly lower rate of complications is observed after cryoablation compared to surgery.
  • Cryoablation of abdominal wall endometriosis presents similar effectiveness to surgery alone.
  • A significant reduction of pain is observed 6 months after treatment.
  • A significant reduction of abdominal wall endometriosis is observed at 6 months.

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